Macrophage Activation State Markers

M1
M1
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IFN-gamma, LPS, OxLDL,
Cholesterol crystals
IFN-gamma, LPS, OxLDL,
Cholesterol crystals
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Cytokines
Cytokines
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IL-1 beta
IL-1 beta
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IL-6
IL-6
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IL-12high
IL-12high
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IL-15
IL-15
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IL-17
IL-17
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IL-18
IL-18
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IL-23
IL-23
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IFN-gamma
IFN-gamma
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TNF-alpha
TNF-alpha
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Chemokines
Chemokines
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CCL2-CCL5
CCL2-CCL5
CCL8
CCL8
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CCL11
CCL11
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CCL15 (human)
CCL15 (human)
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CCL19
CCL19
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CCL20
CCL20
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CXCL1-CXCL3
CXCL1-CXCL3
CXCL5
CXCL5
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CXCL8-CXCL11
CXCL8-CXCL11
CXCL13
CXCL13
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CXCL16
CXCL16
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CX3CL1
CX3CL1
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Cytokines/Growth Factors
Cytokines/Growth Factors
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B7-1/CD80
B7-1/CD80
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B7-2/CD86
B7-2/CD86
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CD36/SR-B3
CD36/SR-B3
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CD68/SR-D1
CD68/SR-D1
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Fc gamma RII/CD32
Fc gamma RII/CD32
Fc gamma RIII/CD16
Fc gamma RIII/CD16
IFN-gamma R
IFN-gamma R
MHC class IIhigh
MHC class IIhigh
COX-2
COX-2
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iNOS
iNOS
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IRF5
IRF5
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STAT1
STAT1
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Negative Marker
Negative Marker
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CD163-
CD163-
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M2a
M2a
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IL-4, IL-13
IL-4, IL-13
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Chemokines
Chemokines
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CCL1-CCL2
CCL1-CCL2
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CCL14 (human)
CCL14 (human)
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CCL17-CCL18
CCL17-CCL18
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CCL22
CCL22
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CCL23 (human)
CCL23 (human)
CCL24
CCL24
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CCL26
CCL26
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YM1/Chitinase 3-like 3 (mouse)
YM1/Chitinase 3-like 3 (mouse)
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Cytokines/Growth Factors
Cytokines/Growth Factors
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FIZZ1/RELM alpha
FIZZ1/RELM alpha
IL-1rahigh
IL-1rahigh
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IL-10high
IL-10high
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IL-12low
IL-12low
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TGF-beta
TGF-beta
Cytokines/Growth Factors
Cytokines/Growth Factors
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CD163
CD163
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CD200 R1
CD200 R1
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CLEC10A/CD301
CLEC10A/CD301
CXCR1
CXCR1
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CXCR2
CXCR2
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DC-SIGN/CD209
DC-SIGN/CD209
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Dectin-1
Dectin-1
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Fc epsilon RI alpha
Fc epsilon RI alpha
IL-1 RII
IL-1 RII
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IL-4 R alpha
IL-4 R alpha
MHC class IIlow
MHC class IIlow
MMR/CD206
MMR/CD206
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Arginase 1 (mouse)
Arginase 1 (mouse)
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IRF4
IRF4
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PPAR gamma
PPAR gamma
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STAT6
STAT6
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M2b
M2b
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Immune Complex, IL-1 R/TLR Ligands
Immune Complex, IL-1 R/TLR Ligands
Chemokines
Chemokines
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CCL1
CCL1
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CCL20
CCL20
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CXCL1-CXCL3
CXCL1-CXCL3
Cytokines
Cytokines
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G-CSF
G-CSF
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GM-CSF
GM-CSF
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IL-1 beta
IL-1 beta
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IL-6
IL-6
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IL-10
IL-10
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TNF-alpha
TNF-alpha
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Cytokines/Growth Factors
Cytokines/Growth Factors
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B7-2/CD86
B7-2/CD86
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IL-4 R alpha
IL-4 R alpha
MHC class II
MHC class II
COX-2
COX-2
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SOCS-3
SOCS-3
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SPHK1/2
SPHK1/2
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IRF4
IRF4
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M2c
M2c
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IL-10, TGF-beta,
Glucocorticoid Hormones
IL-10, TGF-beta,
Glucocorticoid Hormones
Chemokines
Chemokines
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CCL16
CCL16
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CCL18
CCL18
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CXCL13
CXCL13
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Cytokines
Cytokines
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IL-10
IL-10
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TGF-beta
TGF-beta
Cytokines/Growth Factors
Cytokines/Growth Factors
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CCR2
CCR2
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CD150/SLAM
CD150/SLAM
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CD163
CD163
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IL-4 R alpha
IL-4 R alpha
MMR/CD206
MMR/CD206
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SR-AI/MSR
SR-AI/MSR
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SR-BI
SR-BI
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TLR1
TLR1
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Arginase 1 (mouse)
Arginase 1 (mouse)
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SOCS-3
SOCS-3
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TLR8
TLR8
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IRF4
IRF4
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M2d
M2d
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TLR Agonists + Adenosine
TLR Agonists + Adenosine
Chemokines
Chemokines
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CCL5
CCL5
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CXCL10
CXCL10
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CXCL16
CXCL16
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Cytokines
Cytokines
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IL-10
IL-10
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IL-12low
IL-12low
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TNF-alphalow
TNF-alphalow
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VEGF
VEGF
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iNOS
iNOS
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Macrophage
Activation
States
Macrophage
Activation
States
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Data Examples

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Macrophage Activation State Markers background image 1