Evolution of Model Systems for Toxicology, Drug Screening, and Disease Modeling

This eBook provides a primer on the history, current state, and future use of cell based 2D and 3D model systems for toxicology, drug screening, and disease modeling. Included are chapters on primary cells, cell lines, stem cells, 3D cell culture models, and more complex tissue and organ modeling systems.

Key Topics

• Primary and cell lines for toxicology
• Pluripotent stem cell models
• 2D vs. 3D cell culture
• Organoid benefits and challenges
• Future models and challenges
• Toxicology assays

Infographics and Interactive Features for Cell Culture Models

• ADME/Tox specifications
• Commonly-used cell lines, categorized by organ
• 2D vs. 3D model systems
• Organoid reagent guide

Related Information

App Note: Optimizing Organoid Culture Conditions: The Importance of Growth Factor Bioactivity and Reagent Consistency

Organoid and 3D Cell Culture Resources and Reagents

Induced Pluripotent Stem Cell (iPSC) Reagents

Cultrex Basement Membrane Extracts and Extracellular Matrices

App Note: The Importance of Consistency in Fetal Bovine Serum