3-D Matrices and Assay Kits

Organoid and three dimensional (3-D) cell culture systems are emerging as pivotal models for regenerative medicine, drug discovery, toxicology, and cancer research. Organoids are generated from pluripotent stem cells or organ progenitor cells that have differentiated and self-organized into a formation that resembles the structure and function of an intact mammalian organ. The in vitro generation of organoids requires an extracellular matrix that provides a growth scaffold with optimal tensile strength and molecular composition, including laminin, collagen IV, entactin, and heparin sulfate proteoglycan. R&D Systems has partnered with Trevigen® to offer a range of Cultrex® Basement Membrane Extracts that are ideal for generating organoid and 3-D cultures from pluripotent stem cells and cancer stem cells.