Blood-Brain Barrier and Immune Cell Transmigration

The blood-brain barrier is a selective diffusion barrier that lies between the peripheral circulation and central nervous system. During prolonged inflammatory conditions, the blood-brain barrier will breakdown and allow infiltration of peripheral immune cells into the central nervous system. This brochure provides:

  • A detailed schematic outlining the breakdown of the blood-brain barrier.
  • A listing of antibodies that can be used for the detection of the cell types involved in mediating inflammatory responses in neural tissue.
  • A listing of immunoassays for the measurement of cytokine levels.
  • Verification data for select products.