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Angiopoietin-like Protein 3/ANGPTL3: Products

Angiopoietin-like Protein 3 (ANGPTL3) is a secreted glycoprotein that is primarily expressed in the liver. Full length ANGPTL3 circulates in the plasma as do the proteolytically separated N- and C-terminal fragments containing the coiled coil domain and fibrinogen-like domains, respectively. ANGPTL3 directly inhibits lipoprotein lipase (LPL) and endothelial lipase (EL), enzymes responsible for hydrolyzing circulating triglycerides and HDL phospholipids. It promotes an increase in circulating triglyceride levels without altering VLDL or HDL secretion or uptake. ANGPTL3 is upregulated by LXR agonists and downregulated by Insulin, Leptin, and agonists of TR beta or PPAR beta. Its fibrinogen-like domain interacts with Integrin alphaV beta3 to induce endothelial cell adhesion, migration, and neovascularization. ANGPTL3 also promotes the expansion of hematopoietic stem cells.

Showing 1-5 out of 5 Angiopoietin-like Protein 3/ANGPTL3 Products

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Proteome Profiler Mouse XL Cytokine Array


Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
ARY0283  
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Proteome Profiler Mouse Angiogenesis Array Kit


Contains 4 membranes - each spotted in duplicate with 53 different angiogenesis antibodies
ARY01531  
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Proteome Profiler Mouse Adipokine Array Kit


Contains 4 membranes - each spotted in duplicate with 38 different obesity-related antibodies
ARY0137  
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Proteome Profiler Human Adipokine Array Kit


Contains 4 membranes-each spotted in duplicate with 58 different obesity-related antibodies
ARY0241  
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Proteome Profiler Rat Adipokine Array Kit


Contains 4 membranes - each spotted in duplicate with 30 different obesity-related antibodies
ARY016 
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