Filter Results
clear

By Category

By Common Name

clear

By Citation

clear

By Brand

CXCL4/PF4: Products

CXCL4/PF4 is a secreted chemokine that is expressed by megakaryocytes and restrains the coagulation cascade. It is released by activated platelets and regulates Thrombin/Thrombomodulin complexes, activated Protein C (APC), Coagulation Factor Xa, and Fibrin. The anticoagulant heparin neutralizes CXCL4 procoagulant effects. Complexes of heparin and CXCL4 trigger antibody formation that causes the pathological syndrome HITT. Immunogenic complexes of CXCL4 with Apolipoprotein H contribute to antiphospholipid syndrome (APS). CXCL4 interferes with the proliferative and angiogenic functions of FGF-2 and VEGF. However, it can also exert proinflammatory and pro-atherogenic effects on monocytes, macrophages, and endothelial cells. CXCL4 may signal through CXCR3B in humans.

Showing 1-3 out of 3 CXCL4/PF4 Products

page of 1
Results Per Page
DescriptionApplicationCat#CitationsImages 

Proteome Profiler Human Angiogenesis Array Kit


Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies
ARY00766  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Proteome Profiler Human XL Cytokine Array Kit


Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
ARY022B11  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Proteome Profiler Human Chemokine Array Kit


Contains 4 membranes - each spotted in duplicate with 31 different chemokine antibodies
ARY0177  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
page of 1
Results Per Page