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FGF basic: Products

 

FGF basic (FGF-2) is a growth factor that functions in angiogenesis, wound healing, tissue repair, learning and memory, and the morphogenesis of heart, bone, and brain. It is upregulated in response to inflammatory stimuli and in many tumors. FGF basic binds to FGF R1c and 2c. Its bioactivity is modulated by a number of other binding partners including heparin, Integrin alpha V beta 3, soluble FGF R1, FGF-BP, free gangliosides, Thrombospondin, Pentraxin 3/TSG-14, Fibrinogen, alpha 2-Macroglobulin, PDGF, and CXCL4/PF4. These molecules act as cellular coreceptors or adhesion partners, extracellular matrix decoys or reservoirs, and soluble scavengers or chaperones. In particular, the interaction of FGF basic with cell surface heparan sulfate proteoglycans (HSPG) is required for the binding and activation of FGF receptors.

 

Showing 1-4 out of 4 FGF basic Products

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Proteome Profiler Human Angiogenesis Array Kit


Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies
ARY00766  
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Proteome Profiler Human XL Cytokine Array Kit


Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
ARY022B11  
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Proteome Profiler Human Adipokine Array Kit


Contains 4 membranes-each spotted in duplicate with 58 different obesity-related antibodies
ARY0241  
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Proteome Profiler Human XL Oncology Array


Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies
ARY0261  
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