15-PGDH/HPGD: Products

HPGD, or 15-hydroxyprostaglandin dehydrogenase, is a NAD+-linked dehydrogenase that oxidizes the hydroxyl group at position 15 of prostaglandins to a ketone, resulting in a loss of biological activity. HPGD is a major enzyme for the catabolism of prostaglandins. The enzyme is a member of the short-chain alcohol dehydrogenase family of enzymes. HPGD is a cytosolic enzyme expressed in most tissues, with highest expression levels in placenta, lung, and kidney. It is inhibited by aspirin and nonsteroidal anti-inflammatory drugs. Defects in HPGD are a cause of hypertrophic osteoarthropathy.

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Human 15-PGDH/HPGD Antibody

SW, WBAF5660 
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Recombinant Human 15-PGDH/HPGD Protein, CF

 5660-DH 
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SW 033291


High affinity 15-PGDH inhibitor; promotes hematopoiesis and hepatocyte proliferation
5759 
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