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4-1BB/TNFRSF9/CD137: Products

4-1BB, also known as CD137 and TNFRSF9, is a transmembrane TNF receptor superfamily member that is expressed as on various populations of activated T cell including CD4+, CD8+, memory CD8+, NKT, and regulatory T cells as well as on myeloid and mast cell progenitors, dendritic cells, mast cells, and bacterially infected osteoblasts. 4-1BB binding by 4-1BB Ligand costimulates T cell proliferation, activation, and/or survival and can enhance the activation-induced cell death of repetitively stimulated T cells. 4-1BB can associate with OX40 on activated T cells, forming a complex that responds to either ligand and inhibits Treg and CD8+ T cell proliferation. Reverse signaling through 4-1BB Ligand inhibits the development of dendritic cells, B cells, and osteoclasts but supports mature dendritic cell survival and costimulates the proliferation and activation of mast cells.

Showing 1-23 out of 23 4-1BB/TNFRSF9/CD137 Products

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Human Magnetic Luminex Assay

LXSAHM8  
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Human Luminex Assay

LXSAH4  
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Human 4-1BB/TNFRSF9/CD137 Antibody

ELISA(Cap), Flow, Func, ICC/IF, IHC, WBAF8383  
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Recombinant Human 4-1BB/TNFRSF9 Fc Chimera Protein, CF

 838-4B3  
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Recombinant Mouse 4-1BB/TNFRSF9 Fc Chimera Protein, CF

 937-4B1  
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Human 4-1BB/TNFRSF9/CD137 Biotinylated Antibody

ELISA(Det), Flow, ICC/IF, WBBAF8381  
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Mouse 4-1BB/TNFRSF9/CD137 Antibody

Flow, Func, IHC, WBAF9372  
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Mouse 4-1BB/TNFRSF9/CD137 Antibody

FuncMAB93712  
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Mouse 4-1BB/TNFRSF9/CD137 Antibody

ELISA(Cap), Flow, WBMAB937 
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Human 4-1BB/TNFRSF9/CD137 Antibody

Flow, WBMAB838 
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Mouse 4-1BB/TNFRSF9/CD137 Biotinylated Antibody

ELISA(Det), Flow, WBBAF937 
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Rat 4-1BB/TNFRSF9/CD137 Antibody

Flow, ICC/IFAF9029 
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Human 4-1BB/TNFRSF9 DuoSet ELISA

ELISADY8383  
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Mouse 4-1BB/TNFRSF9/CD137 PE-conjugated Antibody

FlowFAB937P 
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Human 4-1BB/TNFRSF9/CD137 PE-conjugated Antibody

FlowFAB838P 
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Mouse 4-1BB/TNFRSF9/CD137 Antibody

B/N, WBMAB9372 
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Recombinant Human 4-1BB/TNFRSF9 His-tag Protein, CF

 9220-4B 
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Mouse 4-1BB/TNFRSF9 DuoSet ELISA

ELISADY9371  
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Cynomolgus Monkey 4-1BB/TNFRSF9 XP_005544945 VersaClone cDNA

RDC1629 
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Rat 4-1BB/TNFRSF9/CD137 (NP_001020944) VersaClone cDNA

RDC0362 
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Mouse 4-1BB/TNFRSF9/CD137 (NP_035742) VersaClone cDNA

RDC1514 
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Human 4-1BB/TNFRSF9/CD137 (NP_001552) VersaClone cDNA

RDC1292 
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Recombinant Rat 4-1BB/TNFRSF9 Fc Chimera Protein, CF

 7968-4B 
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