5-HT1D: Products

5-HT1D is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of 5-HT1D is mediated by G proteins that inhibit adenylate cyclase activity. There is an association between polymorphisms within the genes encoding 5-HT1D and 5-HT1B with anorexia nervosa (AN). mRNA concentrations of the 5-HT1D receptor and the transcription factors, NUDR and REST, were significantly increased in dorsal raphe nucleus-captured neurons of female major depressive disorder subjects.

Showing 1-15 out of 15 5-HT1D Products

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Ketanserin tartrate


Selective 5-HT2A antagonist. Also antagonist at 5-HT1D
090812  
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Metergoline


5-HT2 antagonist. Also 5-HT1 antagonist and 5-HT1D ligand. Has moderate affinity for 5-HT6 and high affinity for 5-HT7
05901  
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PNU 142633


Highly selective 5-HT1D agonist
1985 
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GR 127935 hydrochloride


Potent, selective 5-HT1B/1D antagonist
14774  
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DV 7028 hydrochloride


Selective 5-HT2A antagonist; antithrombotic
4480 
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CP 135807


Selective 5-HT1D agonist
3783 
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BRL 15572 hydrochloride


Selective h5-HT1D antagonist
12071  
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Rizatriptan benzoate


Potent 5-HT1B/1D agonist
5136 
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L-694,247


5-HT1D agonist
07811  
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LY 310762 hydrochloride


5-HT1D-preferring antagonist
30781  
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L-703,664 succinate


Selective 5-HT1D receptor agonist
2640 
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GR 46611


5-HT1D agonist
0864 
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Zolmitriptan


Potent 5-HT1B/1D/1F agonist
4657 
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PNU 109291


Potent and selective 5-HT1D agonist
25561  
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Human 5-HT1D (NP_000855) VersaClone cDNA

RDC0285 
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