5-HT1D Receptor Antagonists: Products

5-HT1D is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of 5-HT1D is mediated by G proteins that inhibit adenylate cyclase activity. There is an association between polymorphisms within the genes encoding 5-HT1D and 5-HT1B with anorexia nervosa (AN). mRNA concentrations of the 5-HT1D receptor and the transcription factors, NUDR and REST, were significantly increased in dorsal raphe nucleus-captured neurons of female major depressive disorder subjects.

Showing 1-4 out of 4 5-HT1D Receptor Antagonists Products

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GR 127935 hydrochloride


Potent, selective 5-HT1B/1D antagonist
14774  
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LY 310762 hydrochloride


5-HT1D-preferring antagonist
30781  
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LY 393558


Dual 5-HT1B/1D antagonist and 5-HT re-uptake inhibitor
3350 
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BRL 15572 hydrochloride


Selective h5-HT1D antagonist
12071  
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