5-HT1F Receptor Agonists: Products

5-HT1F is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Serotonin 5-HT1F receptors are located primarily in the hippocampus, cortex and dorsal raphe nucleus. Abnormal function of the serotonergic system has been implicated in a variety of neurologic and psychiatric diseases. 5-HT1F may play a role in these diseases.

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LY 344864 hydrochloride


Potent, selective 5-HT1F agonist
24511  
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LY 334370 hydrochloride


Selective 5-HT1F agonist
30791  
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Zolmitriptan


Potent 5-HT1B/1D/1F agonist
4657 
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