5-HT2A Receptor Antagonists: Products

5-HT2A encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in 5-HT2A are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of 5-HT2A show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene.

Showing 1-25 out of 25 5-HT2A Receptor Antagonists Products

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Clozapine N-oxide


Activator of muscarinic DREADDs. Restrictions apply. See special conditions on product page.
49361  
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Clozapine


Dopamine antagonist with some D4 selectivity. Also 5-HT2A/2C antagonist
044410  
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Ketanserin tartrate


Selective 5-HT2A antagonist. Also antagonist at 5-HT1D
090812  
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Risperidone


5-HT2A antagonist
28651  
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Spiperone hydrochloride


5-HT2A antagonist. Also D2-like antagonist
09953  
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MDL 100907


Potent and selective 5-HT2A antagonist
41732  
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Ziprasidone hydrochloride


5-HT2A/D2 antagonist; atypical antipsychotic
30853  
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Mesulergine hydrochloride


5-HT2A and 5-HT2C antagonist. Also dopamine receptor partial agonist
16441  
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Aripiprazole


High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist
5584 
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DMT


Endogenous sigma1 ligand. Also 5-HT2A agonist. Restrictions apply. See special conditions on product page.
34281  
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AT 1015


Long-acting 5-HT2A antagonist
4468 
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R-96544 hydrochloride


Potent, selective 5-HT2A antagonist
17423  
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Altanserin hydrochloride


5-HT2A receptor antagonist
18092  
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4F 4PP oxalate


Selective 5-HT2A antagonist
05231  
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Sarpogrelate hydrochloride


Selective 5-HT2A antagonist
3739 
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PNU 96415E


D4 and 5-HT2A antagonist; antipsychotic
2735 
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Zotepine


5-HT2A/D2 antagonist; atypical antipsychotic
3996 
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Eplivanserin hemifumarate


Potent and selective 5-HT2A antagonist
4958 
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Paliperidone


Atypical antipsychotic; 5-HT2A and D2 antagonist
4493 
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Fananserin


5-HT2A antagonist. Also D4 antagonist
2645 
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MDL 11,939


5-HT2A antagonist
08706  
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Melperone hydrochloride


5-HT2A/D2 receptor antagonist; neuroleptic
24951  
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EMD 281014 hydrochloride


Selective 5-HT2A antagonist
4470 
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Nefazodone hydrochloride


5-HT2A antagonist and 5-HT uptake inhibitor. Antidepressant
2777 
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DV 7028 hydrochloride


Selective 5-HT2A antagonist; antithrombotic
4480 
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