5-HT1A: Products

5-HT1A is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin(1A) receptors, including 5-HT1A, belong to the family of G protein-coupled receptors and are implicated in the generation and modulation of various cognitive, behavioral and developmental functions. A relationship between 5-HT1A receptors and serotonin transporter (5-HTT) is also suggested by the pathophysiology of depression and the mechanism of action of antidepressants.

Showing 1-26 out of 26 5-HT1A Products

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8-Hydroxy-DPAT hydrobromide


Selective 5-HT1A agonist; also has moderate affinity for 5-HT7
052924
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WAY 100635 maleate


Potent, 5-HT1A silent antagonist. Also D4 agonist
43803
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Aripiprazole


High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist
5584
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Buspirone hydrochloride


5-HT1A partial agonist
09621
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(R)-(+)-8-Hydroxy-DPAT hydrobromide


Selective 5-HT1A agonist. Enantiomer of 8-Hydroxy-DPAT hydrobromide (Cat. No. 0529)
10803
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(S)-WAY 100135 dihydrochloride


Potent, selective 5-HT1A antagonist
12537
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MDL 73005EF hydrochloride


Potent and selective 5-HT1A partial agonist
0411
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MDL 72832 hydrochloride


Potent 5-HT1A ligand
0412
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NAN-190 hydrobromide


5-HT1A antagonist
05533
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BP 554 maleate


Selective 5-HT1A agonist
05561
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8-Hydroxy-PIPAT oxalate


High affinity 5-HT1A agonist
0797
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RU 24969 hemisuccinate


5-HT1B/1A agonist
09121
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MM 77 dihydrochloride


5-HT1A (postsynaptic) antagonist
0933
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Cyanopindolol hemifumarate


5-HT1A/1B antagonist. Also β-adrenergic antagonist
09934
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SDZ 21009


β-adrenoceptor antagonist. Also 5-HT1A/1B antagonist
1516
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Roxindole hydrochloride


Dopamine D2 autoreceptor agonist. Also has affinity for D3, D4, 5-HT1A receptors and the 5-HT transporter
1559
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Nemonapride


Highly potent D2-like antagonist. Also 5-HT1A agonist
1746
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S 14506 hydrochloride


Highly potent 5-HT1A agonist; displays unique binding mechanism
1771
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Urapidil hydrochloride


α1 antagonist. Also 5-HT1A receptor agonist
1772
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Ipsapirone


Selective 5-HT1A agonist
18691
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Xaliproden hydrochloride


Orally active, high affinity 5-HT1A agonist
2491
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Tandospirone hydrochloride


Selective 5-HT1A partial agonist
2854
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NAD 299 hydrochloride


Selective, high affinity 5-HT1A antagonist
3282
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ATC 0175 hydrochloride


MCH1 antagonist; also 5-HT2B antagonist and 5-HT1A partial agonist
3346
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Sumatriptan succinate


5-HT1A/1B/1D receptor agonist
3586
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Human 5-HT1A (NP_000515) VersaClone cDNA

RDC0283 
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