AMPK Activators: Products

AMP-activated protein kinase (AMPK) is a heterotrimeric complex consisting of a catalytic a subunit and regulatory beta and gamma subunits. Each subunit exists as alternate isoforms (alpha 1, alpha 2, beta 1, beta 2, gamma 1, gamma 2, gamma 3), with all 12 combinations capable of forming complexes. The catalytic a subunit of AMPK is activated allosterically by AMP and by phosphorylation via the AMPK kinase LKB1. Active AMPK downregulates anabolic pathways such as fatty acid, triglyceride, and cholesterol synthesis, and up-regulates catabolic pathways such as glycolysis and fatty acid oxidation. AMPK's role in metabolic regulation has implicated this serine/threonine kinase as a therapeutic target in heart disease, obesity, and diabetes.

Showing 1-7 out of 7 AMPK Activators Products

page of 1
Results Per Page
DescriptionApplicationCat#CitationsImages 

Metformin hydrochloride


Activator of LKB1/AMPK; antidiabetic agent
28645  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

AICAR


AMPK activator
284011  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

A 769662


Potent AMPK activator
333615  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

PT 1


AMPK activator
4039 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

RSVA 405


AMPK activator; also STAT3 inhibitor
5138 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Cryptotanshinone


STAT3 inhibitor. Also displays multiple other activities
3713 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

ZLN 024 hydrochloride


Allosteric AMPK activator
5285 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
page of 1
Results Per Page