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AMPK alpha 1: Products

AMP-activated protein kinase (AMPK) is a heterotrimeric complex consisting of a catalytic a subunit and regulatory beta and gamma subunits. Each subunit exists as alternate isoforms (alpha 1, alpha 2, beta 1, beta 2, gamma 1, gamma 2, gamma 3), with all 12 combinations capable of forming complexes. The catalytic a subunit of AMPK is activated allosterically by AMP and by phosphorylation via the AMPK kinase LKB1. Active AMPK downregulates anabolic pathways such as fatty acid, triglyceride, and cholesterol synthesis, and up-regulates catabolic pathways such as glycolysis and fatty acid oxidation. AMPK's role in metabolic regulation has implicated this serine/threonine kinase as a therapeutic target in heart disease, obesity, and diabetes.

Showing 1-11 out of 11 AMPK alpha 1 Products

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DescriptionApplicationCat#CitationsImages 

Metformin hydrochloride


Activator of LKB1/AMPK; antidiabetic agent
28645  
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Dorsomorphin dihydrochloride


Potent AMPK inhibitor
309332  
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Proteome Profiler Human Phospho-Kinase Array Kit


Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 43 different kinases and 2 related total proteins
ARY003B 
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AICAR


AMPK activator
284011  
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Human/Mouse/Rat AMPK alpha 1 Antibody

ICC/IF, IHC, WBAF3197 
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A 769662


Potent AMPK activator
333615  
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Human/Mouse/Rat AMPK alpha 1 Antibody

ICC/IF, SW, WBMAB3197 
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Human/Mouse/Rat Total AMPK alpha 1 DuoSet IC ELISA

ELISADYC3197-2 
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Human Phospho-AMPK alpha 1 (T183) DuoSet IC ELISA

ELISADYC3528-2 
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SAMS Peptide


AMP-activated protein kinase substrate
13441  
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PT 1


AMPK activator
4039 
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