APLP-1: Products

Amyloid Precursor-like Proteins are members of the amyloid precursor protein (APP) superfamily of transmembrane proteins. APLPs show the same structural organization as APP, except APP contains a short Ab sequence associated with Alzheimer’s disease. All family members are proteolytically processed and appear to play a role in neurite outgrowth and copper metabolism. APLPs are proteolytically cleaved by MMPs and secretases, and form both homodimers and heterodimers with APP and other APLPs.

APLP-1 is expressed post-synaptically in cortical neurons. It functions as an adhesion protein through interactions with heparin and collagen I. APLP-1 can be cleaved by gamma-Secretase or Caspases to release intracellular fragments that activate transcription or enhance apoptosis, respectively.

Showing 1-5 out of 5 APLP-1 Products

page of 1
Results Per Page
DescriptionApplicationCat#CitationsImages 

Human APLP-1 Antibody

IHC, IP, WBAF3129 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Human/Mouse APLP-1 Antibody

WBMAB3908 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Human APLP-1 Antibody

Flow, ICC/IFMAB3129 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Mouse APLP-1 Antibody

IP, WBAF3179 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Mouse APLP-1 Biotinylated Antibody

WBBAF3179 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
page of 1
Results Per Page