APLP-1: Products

Amyloid Precursor-like Proteins are members of the amyloid precursor protein (APP) superfamily of transmembrane proteins. APLPs show the same structural organization as APP, except APP contains a short Ab sequence associated with Alzheimer’s disease. All family members are proteolytically processed and appear to play a role in neurite outgrowth and copper metabolism. APLPs are proteolytically cleaved by MMPs and secretases, and form both homodimers and heterodimers with APP and other APLPs.

APLP-1 is expressed post-synaptically in cortical neurons. It functions as an adhesion protein through interactions with heparin and collagen I. APLP-1 can be cleaved by gamma-Secretase or Caspases to release intracellular fragments that activate transcription or enhance apoptosis, respectively.

Showing 1-12 out of 12 APLP-1 Products

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Human APLP-1 Antibody

IHC, IP, WBAF3129 
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Human/Mouse APLP-1 Antibody

WBMAB3908 
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Mouse APLP-1 Antibody

IP, WBAF3179 
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Mouse APLP-1 Biotinylated Antibody

WBBAF3179 
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Human APLP-1 Antibody

CyTOF-ready, Flow, ICC/IFMAB3129 
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Human APLP-1 Alexa Fluor® 488-conjugated Antibody

FlowFAB3129G 
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Human APLP-1 Alexa Fluor® 700-conjugated Antibody

FlowFAB3129N 
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Human APLP-1 Alexa Fluor® 647-conjugated Antibody

FlowFAB3129R 
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Human APLP-1 Alexa Fluor® 750-conjugated Antibody

FlowFAB3129S 
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Human APLP-1 Alexa Fluor® 594-conjugated Antibody

FlowFAB3129T 
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Human APLP-1 Alexa Fluor® 350-conjugated Antibody

FlowFAB3129U 
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Human APLP-1 Alexa Fluor® 405-conjugated Antibody

FlowFAB3129V 
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