Akt (Protein Kinase B) Inhibitors: Products

Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.

Showing 1-8 out of 8 Akt (Protein Kinase B) Inhibitors Products

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API-2


Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral
215111  
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PHT 427


Dual Akt and PDK1 inhibitor; antitumor
4598 
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10-DEBC hydrochloride


Selective Akt/PKB inhibitor
25583  
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Akti-1/2


Potent and selective dual Akt1 and 2 inhibitor
5773 
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FPA 124


Akt/PKB inhibitor
2926 
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API-1


Selective Akt/PKB inhibitor. Antitumor
38972  
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SC 66


Allosteric Akt inhibitor
43981  
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GSK 690693


Akt kinase inhibitor. Antitumor
41443  
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