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Aldehyde Dehydrogenase 1-A1/ALDH1A1: Products

Aldehyde dehydrogenases (ALDHs) are NAD(P)+-dependent enzymes that detoxify aldehydes by oxidizing them to carboxylic acids. Nineteen ALDHs are present in humans, expressed in a variety of organelles and having different substrate preferences. ALDH1A1 is a cytosolic enzyme that preferentially oxidizes retinaldehyde to retinoic acid. ALDH1A1 is expressed in the epithelium of many organs, including brain, liver, testis, eye lens and cornea. ALDH1A1 is highly expressed in brain dopaminergic neurons, where it produces the retinoic acid required for their differentiation and development. The retinoic acid produced by ALDH1A1 is also important for the differentiation of hematopoietic stem cells. ALDH1A1 is a major enzyme in the oxidation of acetaldehyde, a toxic metabolite of ethanol.
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Human/Mouse Aldehyde Dehydrogenase 1‑A1/ ALDH1A1 Antibody

Clonality: Polyclonal
Host: Goat IgG
Applications: IP, Simple Western, IHC, ICC/IF, WB
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AF5869

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Detection of Human and Mouse Aldehyde Dehydrogenase 1-A1/ALDH1A1 by Western Blot.
Aldehyde Dehydrogenase 1-A1/ALDH1A1 in HeLa Human Cell Line.
Aldehyde Dehydrogenase 1-A1/ALDH1A1 in Human Prostate Cancer Tissue.
Detection of Human and Mouse Aldehyde Dehydrogenase 1-A1/ALDH1A1 by Simple Western<SUP>TM</SUP>.

Human Aldehyde Dehydrogenase 1‑A1/
ALDH1A1 Antibody

Clonality: Monoclonal
Host: Mouse IgG2b Clone #703410
Applications: ICC/IF, WB, IHC, Simple Western
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MAB5869

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Detection of Human, Mouse, and Rat Aldehyde Dehydrogenase 1-A1/ALDH1A1 by Western Blot.
Detection of Human Aldehyde Dehydrogenase 1-A1/ALDH1A1 by Simple Western<SUP>TM</SUP>.
Aldehyde Dehydrogenase 1-A1/ALDH1A1 in A549 Human Cell Line.
Aldehyde Dehydrogenase 1-A1/ALDH1A1 in Human Brain.

Recombinant Human Aldehyde Dehydrogenase 1-A1/ALDH1A1, CF

Source: E. coli
Accession #: P00352
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5869-DH

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