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Angiopoietin-like Protein 4/ANGPTL4: Products

Angiopoietin-like 4 (ANGPTL4), also known as FIAF, FARP, and PGAR, is a 55 kDa glycoprotein secreted by the liver and fat tissue. It contains an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain which can be proteolytically separated. The coiled coil domain mediates the formation of variable sized disulfide-linked oligomers. This domain directly inhibits lipoprotein lipase (LPL), resulting in increased circulating triglyceride levels. ANGPTL4 circulates in association with HDL lipoproteins. Its expression in adipose tissue is induced by fasting and suppressed by feeding. In hypoxic areas, ANGPTL4 is induced in both vascular endothelial cells and tumor cells. The N-terminal fragment can function as an angiogenesis inhibitor. In contrast, the C-terminal fragment modulates cell adhesion through interactions with heparan sulfate proteoglycans, Integrins alpha 1 and beta 5, Vitronectin, and Fibronectin, thereby promoting keratinocyte migration and wound healing. ANGPTL4 additionally enhances the survival of hematopoietic and mesenchymal stem cells.

Showing 1-12 out of 12 Angiopoietin-like Protein 4/ANGPTL4 Products

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Human Magnetic Luminex Assay

LXSAHM7  
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Human Luminex Assay

LXSAH4  
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Recombinant Human Angiopoietin-like 4 Protein, CF

 4487-AN4  
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Human Angiopoietin-like 4 DuoSet ELISA

ELISADY348510  
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Human/Primate Angiopoietin-like Protein 4/ANGPTL4 Biotinylated Antibody

ELISA(Det), WBBAF34851  
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Human/Primate Angiopoietin-like Protein 4/ANGPTL4 Antibody

ELISA(Cap), WBAF34851  
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Recombinant Human Angiopoietin-like 4 C-Terminal Frag, CF

 3485-AN1  
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Recombinant Mouse Angiopoietin-like 4 Protein, CF

 4880-AN1  
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Recombinant Human Angiopoietin-like 4 N-Terminal Frag, CF

 8249-AN 
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Recombinant Human Angiopoietin-like 4 Biotin Protein, CF

 BT4487 
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Recombinant Human Angiopoietin-like 4 Biotin Protein, CF


N-Terminal Fragment
 BT8249 
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Proteome Profiler Human XL Oncology Array


Contains 4 membranes-each spotted in duplicate with 84 different cancer-related antibodies
ARY026 
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