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Apoptosis Inducer Compounds

Showing 1-42 out of 42 Apoptosis Inducer Compounds Products

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Cisplatin


Potent pro-apoptotic anticancer agent; activates caspase-3
22519  
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Actinomycin D


Inhibits RNA polymerase
122912  
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Mitomycin C


DNA cross-linking antitumor agent
32582  
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Doxorubicin hydrochloride


Antitumor antibiotic agent. Inhibits DNA topoisomerase II
22528  
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Oxaliplatin


DNA cross-linking antitumor agent
26236  
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Streptozocin


DNA alkylator; antitumor and induces diabetes
1621 
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Triptolide


Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive
32532  
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Curcumin


Antitumor, anti-inflammatory and antioxidant
28411  
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Carboplatin


DNA cross-linking antitumor agent
26262  
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Cyclophosphamide


Alkylating agent; chemotherapeutic
4091 
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Temozolomide


DNA-methylating antitumor agent
27062  
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Betulinic acid


Antitumor and anti-HIV agent; activates NF-kappaB. Also TGR5 agonist
39061  
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C 75


Potent fatty acid synthase inhibitor; proapoptotic
2489 
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FK 866 hydrochloride


Non-competitive and potent NAMPT inhibitor; induces apoptosis and autophagy
4808 
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Fludarabine


Purine analog; inhibits DNA synthesis
34952  
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Apicidin


Potent histone deacetylase inhibitor
4846 
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Kaempferol


Proapoptotic; downregulates PLK1 expression and activates mitochondrial Ca2+ uniporter
36031  
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CHM 1


Potent antitumor agent; inducer of apoptosis
3868 
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SMBA 1


High affinity and selective activator of Bax
5314 
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Bendamustine hydrochloride


Cytostatic agent; exhibits DNA alkylating and purine analog properties
3681 
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CFM 4


CARP-1 mimetic; proapoptotic
5144 
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Cladribine


Deoxyadenosine analog; pro-apoptotic
52921  
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Apoptosis Activator 2


Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis
20981  
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Deguelin


Anticancer and antiviral agent; chemopreventive and pro-apoptotic
17701  
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Embelin


Inhibitor of X-linked inhibitor of apoptosis (XIAP); cell-permeable and antitumor
2156 
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iMDK


Suppressor of MDK expression; inhibits PI 3-K signaling
5126 
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Piperlongumine


Induces apoptosis; increases p53 and ROS levels in cancer cells
43961  
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2,3-DCPE hydrochloride


Selectively induces cancer cell apoptosis
2137 
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Plumbagin


Induces G2/M cell cycle arrest; anticancer
4761 
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UC 112


IAP and XIAP inhibitor; antitumor
5251 
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NSC 687852


Inhibitor of UCHL5 and USP14
4566 
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Oncrasin 1


Induces abnormal nuclear aggregation of PKCι; proapoptotic
3427 
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Gambogic acid


Apoptosis inducer. Activates caspases and inhibits Bcl-2 family proteins
35902  
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Narciclasine


Antiproliferative agent; slows cell cycle progression
3715 
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PCI 34051


Potent and selective HDAC8 inhibitor
4643 
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2-Methoxyestradiol


Apoptotic and antiangiogenic agent
1807 
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AT 101


Downregulates Bcl-2 and Mcl-1; pro-apoptotic
33671  
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BAM 7


Selective Bax activator; induces Bax-mediated apoptosis
4810 
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CHMFL-FLT3-122


Potent and selective FLT3 inhibitor
5800 
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Chaetoglobosin A


Antibiotic; selective apoptosis inducer of CLL cells
5804 
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TW 37


Bcl-2 inhibitor; induces apoptosis
4038 
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Oleanolic acid


Selective GPBA receptor (TGR5) partial agonist
6026 
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