Aurora Kinase Inhibitors: Products

The mammalian Aurora kinase family contains three serine/threonine kinase members that participate in cell division. They impact cytokinesis and chromatid segregation during the G2/M phase of cell division. Aurora A influences centrosome maturation and spindle assembly, while Auroras B and C direct chromosome alignment and segregation.

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ZM 447439


Inhibits Aurora kinase B
245826
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Hesperadin hydrochloride


Potent Aurora kinase B inhibitor
3988
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TC-A 2317 hydrochloride


Potent, selective Aurora kinase A inhibitor
4066
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CCT 137690


Potent pan-Aurora kinase inhibitor
4291
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SNS 314 mesylate


Potent pan-Aurora kinase inhibitor
4584
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PF 03814735


Aurora kinase A and B inhibitor
4821
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TC-S 7010


Potent and selective Aurora kinase A inhibitor
5286
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VX 680


High affinity and selective Aurora kinase inhibitor
5907
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