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Autophagy-related Compounds

Showing 1-46 out of 46 Autophagy-related Compounds Products

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Dorsomorphin dihydrochloride


Potent AMPK inhibitor
309332  
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Bafilomycin A1


H+-ATPase (vacuolar) inhibitor
133425  
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Thapsigargin


Potent inhibitor of SERCA ATPase
113826  
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Taxol


Promotes assembly and inhibits disassembly of microtubules
109716  
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Torin 1


Potent and selective mTOR inhibitor
424758  
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Rapamycin


mTOR inhibitor; immunosuppressant
129230  
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Dexamethasone


Anti-inflammatory glucocorticoid
11263  
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Valproic acid, sodium salt


Histone deacetylase inhibitor
28152  
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LY 294002 hydrochloride


Prototypical PI 3-kinase inhibitor; also inhibits other kinases
113059  
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Chloroquine diphosphate


Antimalarial; inhibits apoptosis and autophagy
4109 
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Tunicamycin


Antibiotic; GlcNAc phosphotransferase inhibitor
35161  
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NF 449


Highly selective P2X1 antagonist
139112  
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Pepstatin A


Aspartic protease inhibitor
11901  
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GF 109203X


Protein kinase C inhibitor
074128  
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Wortmannin


Potent, irreversible inhibitor of PI 3-kinase. Also inhibitor of PLK1
123240  
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Brefeldin A


Disrupts protein translocation to Golgi
12313  
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(±)-Bay K 8644


Ca2+ channel activator (L-type)
15446  
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Rottlerin


Reported PKCdelta inhibitor
16103  
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Verapamil hydrochloride


Ca2+ channel blocker (L-type)
06546  
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PI 103 hydrochloride


Inhibitor of PI 3-kinase, mTOR and DNA-PK
29306  
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3-Methyladenine


Class III PI 3-kinase inhibitor; also inhibits autophagy
39774  
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A23187, free acid


Calcium ionophore
12346  
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Temozolomide


DNA-methylating antitumor agent
27062  
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Niclosamide


STAT3 inhibitor; also inhibits mTORC1 signaling
40791  
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SMER 28


Positive regulator of autophagy
42971  
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Pifithrin-α hydrobromide


p53 inhibitor. Also aryl hydrocarbon receptor agonist
12672  
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Nocodazole


Microtubule inhibitor
12287  
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Concanamycin A


H+-ATPase (vacuolar) inhibitor
2656 
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FK 866 hydrochloride


Non-competitive and potent NAMPT inhibitor; induces apoptosis and autophagy
4808 
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E 64d


Cathepsin inhibitor; interferes with autolysosomal digestion
4545 
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Vinblastine sulfate


Disrupts microtubules
12562  
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EB 1089


Vitamin D receptor (VDR) agonist
39932  
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Nimodipine


Ca2+ channel blocker (L-type)
060016  
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L-690,330


Inositol monophosphatase inhibitor
06816  
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Nitrendipine


Ca2+ channel blocker (L-type)
06012  
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Amiodarone hydrochloride


Broad spectrum ion channel blocker; antiarrhythmic
40951  
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Salirasib


Ras inhibitor; also induces autophagy
49891  
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Apicidin


Potent histone deacetylase inhibitor
4846 
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Carbamazepine


Inhibitor of neuronal voltage-gated Na+ channels; anticonvulsant
4098 
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3-Nitropropionic acid


Irreversible mitochondrial respiratory complex II inhibitor
4849 
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Xanthohumol


Valosin-containing protein (VCP) inhibitor
4686 
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DBeQ


Selective and reversible p97 ATPase inhibitor
4417 
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MRT 68601 hydrochloride


Potent TBK1 inhibitor
5067 
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GPP 78 hydrochloride


NAMPT inhibitor; also induces autophagy
4835 
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Hydroxychloroquine sulfate


Autophagy inhibitor; also TLR9 inhibitor
5648 
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ML 240


ATP-competitive inhibitor of p97 ATPase
5153 
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