B7-H3: Products

Human B7-H3 was originally identified as a 316 amino acid (aa) type I membrane precursor protein with a putative 28 aa signal peptide, a 217 aa extracellular region containing one V-like and one C-like Ig domain, a transmembrane region, and a 45 aa cytoplasmic domain. Subsequently, a second dominantly expressed form of human B7-H3, containing a splice variation that duplicates the V-like and C-like Ig domains, was found. The 534 aa splice variant of B7-H3 has been referred to as B7-H3b, 4Ig-B7-H3, and B7-H3VCVC. RTPCR transcripts for both B7-H3 and 4Ig-B7-H3 have been found in all tissues except peripheral blood leukocytes. Southern blot analysis indicates that the 4Ig-B7-H3 isoform of B7-H3 is the predominate isoform expressed in human tissues.

In mouse, only a single form of B7-H3 containing one V-like and one C-like Ig domain was detected. Mouse and human B7-H3 share 87% aa sequence identity. B7-H3 has been shown to be expressed at very high levels in immature dendritic cells, at moderate levels on mature dendritic cells, LPS stimulated immature dendritic cells and LPS stimulated monocytes, and at low levels on resting monocytes. B7-H3 binds to activated T cells via an as yet unidentified receptor.

Showing 1-25 out of 25 B7-H3 Products

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Human B7-H3 Antibody

Flow, IHC, SW, WBAF10276  
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Human B7-H3 Antibody

Flow, WBMAB10275  
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Human B7-H3 Biotinylated Antibody

IHC, WBBAF10272  
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Recombinant Human B7-H3 (4Ig)/B7-H3b Protein, CF

 2318-B3/CF 
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Recombinant Human B7-H3 (4Ig)/B7-H3b Protein

 2318-B3 
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Recombinant Human B7-H3 His-tag Protein

 1949-B32  
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Recombinant Human B7-H3 Protein, CF

 1949-B3/CF2  
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Recombinant Human B7-H3 Fc Chimera Protein, CF

 1027-B32  
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Recombinant Mouse B7-H3 Protein

 1397-B33  
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Recombinant Mouse B7-H3 Protein, CF

 1397-B3/CF3  
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Human B7-H3 Quantikine ELISA Kit

ELISADB7H301  
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Human B7-H3 PE-conjugated Antibody

FlowFAB1027P 
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Mouse B7-H3 Antibody

B/N, WBAF13971  
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Human B7-H3 Fluorescein-conjugated Antibody

FlowFAB1027F1  
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Human B7-H3 APC-conjugated Antibody

FlowFAB1027A 
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Human B7-H3 Alexa Fluor® 700-conjugated Antibody

FlowFAB1027N 
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Mouse B7-H3 Biotinylated Antibody

WBBAF1397 
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Human B7-H3 Alexa Fluor® 405-conjugated Antibody

FlowFAB1027V 
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Human B7-H3 Alexa Fluor® 594-conjugated Antibody

FlowFAB1027T 
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Human B7-H3 DuoSet ELISA

ELISADY1949-05 
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Human B7-H3 (NP_001019907) VersaClone cDNA

RDC1542 
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Mouse B7-H3 (NP_598744) VersaClone cDNA

RDC1205 
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Human B7-H3 (NP_079516) VersaClone cDNA

RDC1166 
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Cynomolgus Monkey B7-H3 (XP_005560056) VersaClone cDNA

RDC1385 
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Quantikine Immunoassay Control Set 725 for Human B7-H3


For use with catalog number DB7H30
CtrlQC47 
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