B7-H2: Products

Human B7-H2, also called B7RP-1, B7h, LICOS, and GL50, is a member of the growing B7 family of immune costimulatory proteins. Other family members include B7-1, B7-2, B7-H1 (PD-L1), PD-L2, and B7-H3. B7 proteins are members of the immunoglobulin (Ig) superfamily, the extracellular domains contain 2 Ig-like domains and all members have short cytoplasmic domains. Among the family members, they share about 20-25% amino acid identity. Human and mouse B7-H2 share approximately 49% amino acid identity.

B7-H2 has been identified as the ligand for ICOS, a member of the CD28 family of costimulatory receptors. Human B7-H2 is a 309 amino acid (aa) protein with a putative 18 aa signal peptide, a 239 aa extracellular domain, an 18 aa transmembrane region, and a 33 aa cytoplasmic domain. Human B7-H2 is expressed constitutively on resting B cells, dendritic cells, and at low levels on monocytes. The B7-H2/ICOS interaction appears to play roles in T cell dependent interaction appears to play roles in T cell dependent B cell activation and T Helper (Th) cell differentiation.

Showing 1-24 out of 24 B7-H2 Products

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Human B7-H2 Antibody

CyTOF-ready, Flow, WBAF1652  
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Human B7-H2 Antibody

B/N, CyTOF-ready, FlowMAB1652  
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Human B7-H2 PerCP-conjugated Antibody

FlowFAB165C1  
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Human B7-H2 Alexa Fluor® 700-conjugated Antibody

FlowFAB165N 
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Human B7-H2 PE-conjugated Antibody

FlowFAB165P1  
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Mouse B7-H2 Antibody

CyTOF-ready, Flow, ICC/IFMAB158 
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Mouse B7-H2 Antibody

ICC/IF, WBAF1581  
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Human B7-H2 Biotinylated Antibody

Flow, WBBAF165 
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Human B7-H2 APC-conjugated Antibody

FlowFAB165A 
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Human B7-H2 Antibody

B/N, WBMAB1651 
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Mouse B7-H2 Biotinylated Antibody

WBBAF158 
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Mouse B7-H2 Alexa Fluor® 488-conjugated Antibody

FlowFAB158G 
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Mouse B7-H2 Alexa Fluor® 700-conjugated Antibody

FlowFAB158N 
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Mouse B7-H2 Alexa Fluor® 647-conjugated Antibody

FlowFAB158R 
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Mouse B7-H2 Alexa Fluor® 750-conjugated Antibody

FlowFAB158S 
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Mouse B7-H2 Alexa Fluor® 594-conjugated Antibody

FlowFAB158T 
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Mouse B7-H2 Alexa Fluor® 350-conjugated Antibody

FlowFAB158U 
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Mouse B7-H2 Alexa Fluor® 405-conjugated Antibody

FlowFAB158V 
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Human B7-H2 Alexa Fluor® 488-conjugated Antibody

FlowFAB165G 
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Human B7-H2 Alexa Fluor® 647-conjugated Antibody

FlowFAB165R 
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Human B7-H2 Alexa Fluor® 750-conjugated Antibody

FlowFAB165S 
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Human B7-H2 Alexa Fluor® 594-conjugated Antibody

FlowFAB165T 
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Human B7-H2 Alexa Fluor® 350-conjugated Antibody

FlowFAB165U 
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Human B7-H2 Alexa Fluor® 405-conjugated Antibody

FlowFAB165V 
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