BDNF: Products

BDNF (Brain-Derived Neurotrophic Factor) is a secreted protein that regulates many aspects of neuronal development and function in the nervous system. It is produced as proBDNF in response to neuronal activity or inflammatory stimulation and is then cleaved before associating into a homodimer. It is expressed throughout the nervous system as well as by fibroblasts, megakaryocytes/platelets, and smooth muscle cells. BDNF regulates neural stem cell survival and differentiation, axon/dendrite differentiation, synapse formation and maturation, and refinement of developing circuits. It is also a key regulator of synaptic plasticity and late-phase long-term potentiation. BDNF signals through the TrkB and NGF R/TNFRSF16 receptors. Secreted proBDNF can bind to NGF R/TNFRSF16 and induce long-term depression and cell apoptosis.

Showing 1-5 out of 5 BDNF Products

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Human Free BDNF Quantikine ELISA Kit

ELISADBD0021  
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Total BDNF Quantikine ELISA Kit


Detects free and Trk-bound BDNF
ELISADBNT00 
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Human BDNF DuoSet ELISA

ELISADY24815  
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Quantikine Immunoassay Control Set 885 for Total BDNF


For use with catalog number DBNT00
CtrlQC218 
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Human Pro-BDNF DuoSet ELISA

ELISADY3175 
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