BDNF: Products

BDNF (Brain-Derived Neurotrophic Factor) is a secreted protein that regulates many aspects of neuronal development and function in the nervous system. It is produced as proBDNF in response to neuronal activity or inflammatory stimulation and is then cleaved before associating into a homodimer. It is expressed throughout the nervous system as well as by fibroblasts, megakaryocytes/platelets, and smooth muscle cells. BDNF regulates neural stem cell survival and differentiation, axon/dendrite differentiation, synapse formation and maturation, and refinement of developing circuits. It is also a key regulator of synaptic plasticity and late-phase long-term potentiation. BDNF signals through the TrkB and NGF R/TNFRSF16 receptors. Secreted proBDNF can bind to NGF R/TNFRSF16 and induce long-term depression and cell apoptosis.

Showing 1-12 out of 12 BDNF Products

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Human BDNF Antibody

IHC, WBMAB2488  
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Human BDNF Antibody

MAB8481  
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Human BDNF Antibody

CyTOF-ready, Flow, IHCAF2485  
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Human BDNF Antibody

WBMAB6481  
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Human BDNF Biotinylated Antibody

BAM6481  
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Human BDNF Antibody

CyTOF-ready, FlowMAB24811  
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Human Pro‑BDNF Antibody

IHC, WBMAB31751 
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Human BDNF Biotinylated Antibody

Flow, IHC, WBBAF248 
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Human BDNF APC-conjugated Antibody

FlowIC2481A 
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Human Pro BDNF Antibody

IHCMAB3175 
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Human BDNF PerCP-conjugated Antibody

FlowIC2481C 
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Human BDNF PE-conjugated Antibody

FlowIC2481P 
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