BMP-15/GDF-9B: Products

 

BMP-15 (Bone morphogenetic protein 15), also known as GDF-9B, is a TGF-b superfamily ligand that is expressed by oocytes throughout folliculogenesis and plays an important role in oocyte development. BMP-15 promotes the FSH-independent proliferation of ovarian granulosa cells (GC) and induces GC glycolysis and cholesterol synthesis. BMP-15 blocks the FSH-induced GC expression of FSH R and multiple steroidogenic molecules. BMP-15 exerts is effects through interactions with BMPR-IB/ALK6 and BMPR-II, and nonphosphorylated BMP-15 functions as a competitive antagonist at BMPR-IB . Mature BMP-15 forms 34 kDa noncovalently-linked homodimers and 37 kDa heterodimers with mature GDF-9.

Showing 1-6 out of 6 BMP-15/GDF-9B Products

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Recombinant Human BMP-15 Protein

 5096-BM6  
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Human BMP-15/GDF-9B Antibody

IHC, WBMAB2925 
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Mouse/Rat BMP-15/GDF-9B Antibody

WBAF5917 
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Mouse BMP-15/GDF-9B Antibody

IHCMAB5917 
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Human BMP-15/GDF-9B Biotinylated Antibody

WBBAF2925 
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Human BMP-15/GDF-9B Antibody

WBAF2925 
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