BMP-6: Products

 

BMP-6 (Bone Morphogenetic Protein 6) forms disulfide-linked homodimers and heterodimers with BMP-2 that signal through complexes of type I (Activin RIA/ALK-2 and BMPR-IA/ALK-3) and type II (Activin RIIA and BMPR-II) receptors. BMP-6 promotes osteoblast differentiation from mesenchymal stem cells, chondrocyte maturation, Ang II-induced aldosterone production in the adrenal cortex, and hormone production and responsiveness in ovarian granulosa cells. It promotes neurite outgrowth, neuroprotection, angiogenesis, immune tolerance, and tumor progression. BMP-6 binds to RGM-C/Hemojuvelin to enhance Hepcidin expression and prevent serum iron overload. Heterodimers of BMP-2 and BMP-6 show increased potency at inducing bone formation compared to either BMP-2 or BMP-6 homodimers.

Showing 1-14 out of 14 BMP-6 Products

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Recombinant Human BMP-6 Protein

 507-BP23  
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Recombinant Human BMP-6 Protein, CF

 507-BP/CF23  
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Human BMP-6 Antibody

B/N, ELISA(Cap), WBMAB5072  
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Human BMP-6 Antibody

B/N, IHC, WBAF5073  
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Recombinant Mouse BMP-6 Protein, CF

 6325-BM/CF1  
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Recombinant Mouse BMP-6 Protein

 6325-BM1  
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Mouse BMP-6 Antibody

IHC, WBAF6325 
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Human BMP-6 Biotinylated Antibody

ELISA(Det), WBBAF5072  
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Human BMP-6 DuoSet ELISA

ELISADY5073  
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Mouse BMP-6 Antibody

B/NMAB6325 
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Recombinant Human BMP-6, Biotinylated Protein

 BT507 
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Recombinant Human BMP-6, Biotinylated Protein, CF

 BT507/CF 
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Recombinant Human BMP-2/BMP-6 Heterodimer Protein

 7145-BP 
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Recombinant Human BMP-2/BMP-6 Heterodimer Protein, CF

 7145-BP/CF 
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