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CCL26/Eotaxin-3: Products

CCL26, also known as Eotaxin-3 and SCYA26, is a small cytokine that is a member of the CC chemokine family. It is only 94 amino acids (aa) in length, with aa 1-23 serving as a putative signal peptide. Human CCL26/Eotaxin-3 has a predicted molecular weight of approximately 11 kDa, and the mature protein only shares 27% aa sequence identity with the mouse ortholog. CCL26/Eotaxin-3 is constitutively expressed at low levels in various tissues including in the heart and ovary. Its expression in upregulated in vascular endothelial cells by IL-13 and IL-4. CCL26/Eotaxin-3 is a selective agonist for CCR3, as serves as a chemoattractant for cells that express CCR3, such as eosinophils, basophils, and Th2 cells. It has also been shown to act as an antagonist for the receptors CCR1 and CCR5. CCL26/Eotaxin-3 plays a role in allergic reactions.

Showing 1-4 out of 4 CCL26/Eotaxin-3 Products

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Recombinant Human CCL26/Eotaxin-3 Protein

 653-E32  
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Recombinant Human CCL26/Eotaxin-3 Protein, CF

 653-E3/CF2  
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Recombinant Human CCL26/Eotaxin-3 (aa 24-94) Protein

 346-E32  
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Recombinant Human CCL26/Eotaxin-3 (aa 24-94) Protein, CF

 346-E3/CF2  
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