CCR2: Products

CCR2 is a G protein-coupled receptor member of the CC chemokine subfamily of receptors. Human CCR2 is 374 amino acids (aa) in length with a predicted molecular weight of 42 kDa. Mouse and rat CCR2 share 80% aa sequence identity with the human protein. Most chemokine receptors exhibit promiscuous binding properties whereby several different chemokines signal through the same receptor. Chemokine ligand receptor binding results in G protein activation as well as the activation of downstream signaling cascades, including the Akt and NFkB pathways. Chemokine receptors mediate the chemotactic actions of chemokine ligands and activation of these receptors leads to cytoskeleton rearrangement and chemotactic cell migration.

Showing 1-31 out of 31 CCR2 Products

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Human CCR2 PE-conjugated Antibody


Clone 48607 was used by HLDA to establish CD designation
FlowFAB151P23  
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Mouse CCR2 PE-conjugated Antibody

FlowFAB5538P10  
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Human CCR2 Antibody


Clone 48607 was used by HLDA to establish CD designation
Flow, IHCMAB15021  
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Mouse CCR2 APC-conjugated Antibody

FlowFAB5538A11  
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Mouse CCR2 Fluorescein-conjugated Antibody

FlowFAB5538F6  
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Human CCR2 APC-conjugated Antibody


Clone 48607 was used by HLDA to establish CD designation
FlowFAB151A8  
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Mouse CCR2 Alexa Fluor® 700-conjugated Antibody

FlowFAB5538N 
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RS 504393


Highly selective CCR2 chemokine receptor antagonist
251712  
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Human CCR2 Biotinylated Antibody


Clone 48607 was used by HLDA to establish CD designation
FlowFAB151B5  
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Mouse CCR2 Alexa Fluor® 594-conjugated Antibody

FlowFAB5538T1  
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Human CCR2 Alexa Fluor® 488-conjugated Antibody


Clone 48607 was used by HLDA to establish CD designation
FlowFAB151G2  
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Human CCR2 PerCP-conjugated Antibody


Clone 48607 was used by HLDA to establish CD designation
FlowFAB151C2  
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Mouse CCR2 Alexa Fluor® 647-conjugated Antibody

FlowFAB5538R 
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Mouse CCR2 Alexa Fluor® 750-conjugated Antibody

FlowFAB5538S 
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Human CCR2 Alexa Fluor® 700-conjugated Antibody


Clone 48607 was used by HLDA to establish CD designation
FlowFAB151N1  
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BMS CCR2 22


High affinity, potent CCR2 antagonist
31291  
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RS 102895 hydrochloride


CCR2b chemokine receptor antagonist
20892  
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Rat CCR2 Antibody

FlowMAB8368 
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Rat CCR2 APC-conjugated Antibody

FlowFAB8368A 
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Rat CCR2 PE-conjugated Antibody

FlowFAB8368P 
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Rat CCR2 Alexa Fluor® 647-conjugated Antibody

FlowFAB8368R 
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Rat CCR2 Alexa Fluor® 700-conjugated Antibody

FlowFAB8368N 
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Rat CCR2 Alexa Fluor® 405-conjugated Antibody

FlowFAB8368V 
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INCB 3284 dimesylate


Selective CCR2 antagonist
43063  
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Teijin compound 1


Potent CCR2b antagonist
3664 
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JNJ 27141491


Potent and selective human CCR2 antagonist
5176 
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NVP CXCR2 20


Potent and selective CXCR2 antagonist
5660 
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Human CCR2A (NP_001116513) VersaClone cDNA

RDC0003 
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Rat CCR2 (NP_068638) VersaClone cDNA

RDC0327 
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Human CCR2B (NP_001116868) VersaClone cDNA

RDC0004 
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Mouse CCR2 (NP_034045) VersaClone cDNA

RDC0005 
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