CD109: Products

CD109 is a GPI-anchored member of the alpha-2-macroglobulin (A2M) and complement family of proteins. CD109 is expressed on activated T cells and platelets, hematopoietic stem cells, megakaryocyte precursors, vascular endothelial cells, basal and myoepithelial cells of secretory glands, and squamous cell carcinoma. Human CD109 is produced as a 170 kDa - 180 kDa glycoprotein that is autocatalytically processed to 150 kDa and 120 kDa forms. CD109 on keratinocytes binds TGF-beta and associates with TGF-beta RI and TGF-beta RII, resulting in inhibition of TGF-beta signaling. Polymorphisms of CD109 include the platelet-specific Gov antigen and the blood group ABH antigens. Alloantibodies directed against these antigens result in unsuccessful platelet transfusions, neonatal alloimmune thrombocytopenia, and posttransfusion purpura.

Showing 1-6 out of 6 CD109 Products

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Human CD109 Antibody

Flow, IHCMAB43851  
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Human CD109 Antibody

Flow, IHC, WBAF4385 
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Recombinant Human CD109 Protein, CF

 4385-CD 
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Human/Mouse CD109 PE-conjugated Antibody

FlowFAB4385P 
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Mouse CD109 Antibody

WBAF7717 
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Human CD109 Biotinylated Antibody

WBBAF4385 
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