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CD11b/Integrin alpha M: Products

CD11b, also known as Integrin alpha M and Macrophage-1 Antigen (MAC-1) alpha subunit, is an Integrin alpha chain family member that binds with the Integrin beta 2 subunit, also called CD18, to form the non-covalent heterodimer Integrin alpha M/beta 2, also known as MAC-1 and Complement Receptor Type 3 (CR3). Integrin alpha M/beta 2 is expressed on the surface of many leukocytes including granulocytes, macrophages, dendritic cells, and natural killer cells. It has also been shown to be expressed on microglia, the resident immune cells in the brain. Upon activation, Integrin alpha M/beta 2 binds to several ligands, including ICAM-1, Fibrinogen, and the C3 complement fragment C3bi, to mediate phagocyte adhesion, migration and ingestion of complement-opsonized particles. Human CD11b/Integrin alpha M is 1152 amino acids (aa) in length with a predicted molecular weight of approximately 127 kDa. It contains a N-terminal von Willebrand factor, the type A domain (aa 150-328) and seven FG-GAP repeats, which are thought to be responsible for folding CD11b/Integrin alpha M into a beta propeller structure. Human CD11b/Integrin alpha M shares 74% aa sequence identity with the mouse and rat orthologs.

Showing 1-47 out of 47 CD11b/Integrin alpha M Products

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Mouse CD11b/Integrin alpha M Antibody

CyTOF-reported, Flow, ICC/IF, IHC, IPMAB11249  
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Human CD11b/Integrin alpha M Antibody

CyTOF-reported, Flow, ICC/IF, IHCMAB16993  
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Human CD11b/Integrin alpha M Antibody

WBMAB169925  
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Human/Equine CD11b/Integrin alpha M Antibody

CyTOF-ready, Flow, ICC/IF, IHCMAB16991 
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Mouse CD11b/Integrin alpha M Biotinylated Antibody

Flow, ICC/IF, IHC, IPBAM11242  
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Human/Canine CD11b/Integrin alpha M Antibody

CyTOF-ready, Flow, WBAF16991  
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Human Integrin  alpha M/CD11b PE-conjugated Antibody

FlowFAB16991P1  
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Human Integrin  alpha M/CD11b APC-conjugated Antibody

FlowFAB16991A2  
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Mouse CD11b/Integrin alpha M Antibody

Flow, WBMAB11241 
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Mouse Integrin  alpha M/CD11b PerCP-conjugated Antibody

FlowFAB1124C1  
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Mouse Integrin  alpha M/CD11b Fluorescein-conjugated Antibody

FlowFAB1124F1  
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Mouse Integrin  alpha M/CD11b PE-conjugated Antibody

FlowFAB1124P1  
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Human CD11b/Integrin alpha M Biotinylated Antibody

Flow, IHCBAM1699 
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Human CD11b/Integrin alpha M APC-conjugated Antibody

FlowFAB1699A 
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Human CD11b/Integrin alpha M Alexa Fluor® 488-conjugated Antibody

FlowFAB1699G 
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Human CD11b/Integrin alpha M PE-conjugated Antibody

FlowFAB1699P 
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Mouse Integrin  alpha M/CD11b APC-conjugated Antibody

FlowFAB1124A 
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Human Integrin  alpha M/CD11b PerCP-conjugated Antibody

FlowFAB16991C 
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Human CD11b/Integrin alpha M Alexa Fluor® 700-conjugated Antibody

FlowFAB1699N 
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Leukadherin 1


Allosteric activator of CD11b/CD18
4921 
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Mouse Hematopoietic Lineage Marker Fluorescein Cocktail


500 μL of an Fluorescein-conjugated antibody cocktail of anti-mouse CD3 (Clone 17A2), B220 (Clone RA3-6B2), CD11b (Clone M1/70) Ly-6G/Ly-6C (Gr-1) (Clone RB6-8C5), Ter-119 (Clone TER119), and CD5 (Clone 53-7.3)
FlowFLC001F 
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Mouse Hematopoietic Lineage Marker Alexa Fluor 700 Cocktail


500 μL of an Alexa Fluor 700-conjugated antibody cocktail of anti-mouse CD3 (Clone 17A2), B220 (Clone RA3-6B2), CD11b (Clone M1/70) Ly-6G/Ly-6C (Gr-1) (Clone RB6-8C5), Ter-119 (Clone TER119), and CD5 (Clone 53-7.3)
FlowFLC001N 
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Mouse Hematopoietic Lineage Marker Phycoerythrin Cocktail


500 μL of an PE-conjugated antibody cocktail of anti-mouse CD3 (Clone 17A2), B220 (Clone RA3-6B2), CD11b (Clone M1/70) Ly-6G/Ly-6C (Gr-1) (Clone RB6-8C5), Ter-119 (Clone TER119), and CD5 (Clone 53-7.3)
FlowFLC001P 
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Mouse Hematopoietic Lineage Marker Alexa Fluor 405 Cocktail


500 μL of an Alexa Fluor 405-conjugated antibody cocktail of anti-mouse CD3 (Clone 17A2), B220 (Clone RA3-6B2), CD11b (Clone M1/70) Ly-6G/Ly-6C (Gr-1) (Clone RB6-8C5), Ter-119 (Clone TER119), and CD5 (Clone 53-7.3)
FlowFLC001V 
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Human CD11b/Integrin alpha M (NP_001139280) VersaClone cDNA

RDC0847 
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Mouse CD11b/Integrin alpha M (NP_032427) VersaClone cDNA

RDC1740 
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Mouse CD11b/Integrin alpha M Alexa Fluor® 488-conjugated Antibody

FlowFAB1124G 
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Mouse CD11b/Integrin alpha M Alexa Fluor® 350-conjugated Antibody

FlowFAB1124U 
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Human CD11b/Integrin alpha M Alexa Fluor® 647-conjugated Antibody

FlowFAB1699R 
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Human CD11b/Integrin alpha M Alexa Fluor® 750-conjugated Antibody

FlowFAB1699S 
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Human CD11b/Integrin alpha M Alexa Fluor® 594-conjugated Antibody

FlowFAB1699T 
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Human CD11b/Integrin alpha M Alexa Fluor® 350-conjugated Antibody

FlowFAB1699U 
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Human CD11b/Integrin alpha M Alexa Fluor® 405-conjugated Antibody

FlowFAB1699V 
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Mouse Hematopoietic Lineage Marker Allophycocyanin Cocktail


500 μL of an APC-conjugated antibody cocktail of anti-mouse CD3 (Clone 17A2), B220 (Clone RA3-6B2), CD11b (Clone M1/70) Ly-6G/Ly-6C (Gr-1) (Clone RB6-8C5), Ter-119 (Clone TER119), and CD5 (Clone 53-7.3)
FlowFLC001A 
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Proteome Profiler Human sReceptor Array, Hematopoietic


Contains 4 membranes - 2 spotted in duplicate with 48 different hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
ARY0111  
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