CD161: Products

CD161, also known as KLRB1, NK1.1, and NKR-P1A is a 40 kDa type II transmembrane glycoprotein that contains one C-type lectin domain in its extracellular region. CD161 is expressed as a disulfide-linked dimer on the surface of Th17 cells and NK cells as well as on subsets of CD1-restricted T cells, intestinal NT cells, peripheral memory T cells, monocytes, and dendritic cells. It binds to OCIL/CLEC2d, leading to an inhibition of NK cell-mediated cytotoxicity and IFN-gamma secretion. Alternatively, CD161 can enhance TCR activation to CD1d ligation. CD161+ cell populations are depleted in ulcerative colitis, Grave's disease, and AIDS, although CD161+ T cells are activated during asthmatic attacks. Additional related proteins are expressed in mouse but not human: the inhibitory NKR-P1B and D, and the stimulatory NKR-P1A, C, and F.

Showing 1-6 out of 6 CD161 Products

page of 1
Results Per Page
DescriptionApplicationCat#CitationsImages 

Human CD161 PE-conjugated Antibody

FlowFAB7448P 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Human CD161 APC-conjugated Antibody

FlowFAB7448A 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Human CD161 Alexa Fluor® 488-conjugated Antibody

FlowFAB7448G 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Human CD161 Antibody

FlowMAB7448 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Recombinant Human CD161 Fc Chimera Protein, CF

 7448-CD 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Human CD161 (NP_002249) VersaClone cDNA

RDC1672 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
page of 1
Results Per Page