CD161/NK1.1: Products

CD161, also known as KLRB1, NK1.1, and NKR-P1A is a 40 kDa type II transmembrane glycoprotein that contains one C-type lectin domain in its extracellular region. CD161 is expressed as a disulfide-linked dimer on the surface of Th17 cells and NK cells as well as on subsets of CD1-restricted T cells, intestinal NT cells, peripheral memory T cells, monocytes, and dendritic cells. It binds to OCIL/CLEC2d, leading to an inhibition of NK cell-mediated cytotoxicity and IFN-gamma secretion. Alternatively, CD161 can enhance TCR activation to CD1d ligation. CD161+ cell populations are depleted in ulcerative colitis, Grave's disease, and AIDS, although CD161+ T cells are activated during asthmatic attacks. Additional related proteins are expressed in mouse but not human: the inhibitory NKR-P1B and D, and the stimulatory NKR-P1A, C, and F.

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Mouse CD161/NK1.1 Alexa Fluor® 488‑conjugated Antibody

FlowFAB8319G 
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Mouse CD161/NK1.1 APC-conjugated Antibody

FlowFAB7614A 
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Mouse CD161/NK1.1 Antibody

FlowMAB7614 
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Mouse CD161/NK1.1 Alexa Fluor® 488-conjugated Antibody

FlowFAB7614G 
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Mouse CD161/NK1.1 PE‑conjugated Antibody

FlowFAB8319P 
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Mouse CD161/NK1.1 APC‑conjugated Antibody

FlowFAB8319A 
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Mouse CD161/NK1.1 Alexa Fluor® 700‑conjugated Antibody

FlowFAB8319N 
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Mouse CD161/NK1.1 PE-conjugated Antibody

FlowFAB7614P 
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