CD1a: Products

Cluster of Differentiation 1a (CD1a) is a transmembrane glycoprotein in the CD1 family of MHC-like molecules. It is expressed by most mammals but not by mice or rats. Human CD1a is a 311 amino acid protein with a predicted molecular mass of 49 kDa. It binds to lipid and glycolipid antigens and presents them to T cells. Antigen-presenting cells, Langerhans cells, and thymocytes express CD1a, where it traffics between endosomes and plasma membrane lipid rafts. Heterodimerization with beta-2-Microglobulin is required for CD1a membrane trafficking, and CD1a binding to exogenous lipids results in CD1a protein stability. The activation of thymus-localized T cells during the development of Graves’ disease and Hashimoto’s thyroiditis may be initiated by CD1a expressed by CD83+ dendritic cells.

Showing 1-7 out of 7 CD1a Products

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Human CD1a Antibody

Flow, ICC/IFMAB7076 
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Human CD1a Alexa Fluor® 700-conjugated Antibody

FlowFAB7076N 
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Human CD1a PE-conjugated Antibody

FlowFAB7076P 
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Human CD1a Alexa Fluor® 488-conjugated Antibody

FlowFAB7076G 
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Human CD1a PerCP-conjugated Antibody

FlowFAB7076C 
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Human CD1a APC-conjugated Antibody

FlowFAB7076A 
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Human CD1a (AAA51931) VersaClone cDNA

RDC1192 
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