CDC2/CDK1: Products

CDC2 (Cell Division Cycle 2), also known as CDK1 (Cyclin Dependent Kinase 1), is a member of the CDK family of serine/threonine kinases. The CDKs are important regulators of cell cycle progression and their activities are largely controlled by association with Cyclins, and activating and inhibitory phosphorylations. Entry into mitosis is initiated by CDC2. Full activation of CDC2 requires phosphorylation at T161 and association with CyclinB. In contrast, phosphorylation of CDC2 at Y15 and T14 during the G2-phase of the cell cycle inhibits activity, and dephosphorylation of Y15 and T14 by CDC25 phosphatase during late G2 restores activity.

Showing 1-6 out of 6 CDC2/CDK1 Products

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Human/Mouse/Rat Phospho-CDC2/CDK1 (Y15) Antibody

ICC/IF, WBAF8882  
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Ro 3306


Cyclin-dependent kinase (cdk) 1 inhibitor
41814  
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NU 2058


Cdk1 and cdk2 inhibitor
31351  
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AZD 5438


Potent cyclin-dependent kinase (cdk) 1, 2 and 9 inhibitor
39682  
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(R)-CR8


Dual cdk1/cdk5 inhibitor; also inhibits CK1
36056  
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Roscovitine


Potent, selective cyclin-dependent kinase inhibitor
1332 
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