COX-1: Products

Cyclooxygenase (COX), also known as prostaglandin G/H synthase, is a membrane bound enzyme partly responsible for the catalysis of prostanoid synthesis. COX is expressed as at least three different isoforms. COX-1 is constitutively expressed and thought to regulate a number of 'housekeeping' functions such as vascular hemostasis, renal blood flow, and glomerular function. COX-2 expression is tightly regulated and induced by inflammatory mediators such as growth factors, cytokines, and endotoxin. COX-3 appears to be much more strictly regulated spatially and is observed in greatest abundance in cerebral cortex.

Showing 1-17 out of 17 COX-1 Products

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Indomethacin


Cyclooxygenase inhibitor (COX-1 > COX-2)
17085  
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Resveratrol


Cyclooxygenase inhibitor
14187  
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Human/Mouse COX-1 Antibody

WBMAB37401 
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Flufenamic acid


Activates TRPC6; NSAID
4522 
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(S)-(+)-Ibuprofen


Cyclooxygenase inhibitor (COX-1 > COX-2)
2796 
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Diclofenac sodium salt


Cyclooxygenase inhibitor; NSAID
4454 
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Piroxicam


Cyclooxygenase-1 (COX-1) inhibitor
0960 
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Aspirin


Cyclooxygenase inhibitor; NSAID
40922  
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Human COX-1 Antibody

Flow, WBMAB3740 
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NCX 466


Cyclooxygenase-inhibiting nitric oxide donor
4537 
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Tenidap


NSAID, cyclooxygenase (COX-1) inhibitor. Also opener of KIR2.3
2580 
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Naproxen sodium


Cyclooxygenase inhibitor
2655 
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NCX 4040


NO-donating aspirin; anti-inflammatory and antitumor
4531 
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Sulindac


Cyclooxygenase inhibitor (following metabolism to sulindac sulfide)
17071  
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SC 560


Cyclooxygenase-1 (COX-1) inhibitor
1550 
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Flurbiprofen


Cyclooxygenase inhibitor
1769 
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FR 122047 hydrochloride


Cyclooxygenase (COX-1) inhibitor
15076  
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