CTLA-4: Products

CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.

Showing 1-19 out of 19 CTLA-4 Products

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Human CTLA-4 Antibody

CyTOF-ready, Flow, ICC/IF, WBAF-386-PB1  
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Mouse CTLA-4 Antibody

B/N, CyTOF-ready, Flow, WBMAB4341  
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Human CTLA-4 Antibody

WBMAB3252  
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Mouse CTLA-4 Antibody

ELISA(Cap), WBAF4761  
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Human CTLA-4 PE-conjugated Antibody

FlowFAB386P2  
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Human CTLA-4 Biotinylated Antibody

WBBAF3861  
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Mouse CTLA-4 Biotinylated Antibody

ELISA(Det), WBBAF476 
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Mouse CTLA-4 Fluorescein-conjugated Antibody

FlowFAB434F1  
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Human CTLA-4 APC-conjugated Antibody

FlowFAB386A 
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Mouse CTLA-4 APC-conjugated Antibody

FlowFAB434A 
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Mouse CTLA-4 PE-conjugated Antibody

FlowFAB434P 
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Human CTLA-4 Antibody

FlowMAB3251 
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Mouse CTLA-4 Alexa Fluor® 488-conjugated Antibody

FlowFAB434G 
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Mouse CTLA-4 Alexa Fluor® 700-conjugated Antibody

FlowFAB434N 
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Mouse CTLA-4 Alexa Fluor® 647-conjugated Antibody

FlowFAB434R 
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Mouse CTLA-4 Alexa Fluor® 750-conjugated Antibody

FlowFAB434S 
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Mouse CTLA-4 Alexa Fluor® 594-conjugated Antibody

FlowFAB434T 
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Mouse CTLA-4 Alexa Fluor® 350-conjugated Antibody

FlowFAB434U 
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Mouse CTLA-4 Alexa Fluor® 405-conjugated Antibody

FlowFAB434V 
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