CTLA-4: Products

CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.

Showing 1-11 out of 11 CTLA-4 Products

page of 1
Results Per Page
DescriptionApplicationCat#CitationsImages 
Flow, ICC/IF, WBAF-386-PB1  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
B/N, Flow, WBMAB4341  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
WBMAB3252  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
FlowFAB386P1  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
ELISA(Cap), WBAF4761  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
WBBAF3861  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
ELISA(Det), WBBAF476 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
FlowFAB434F1  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
FlowFAB386A 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
FlowFAB434P 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
FlowFAB434A 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
page of 1
Results Per Page