CTLA-4: Products

CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.

Showing 1-6 out of 6 CTLA-4 Products

page of 1
Results Per Page
DescriptionApplicationCat#CitationsImages 

Recombinant Human CTLA-4 Fc Chimera (CHO-expressed), CF

 7268-CT1  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Recombinant Human CTLA-4 Fc Chimera His Tagged Protein


New rhCTLA-4 Available! Increased activity; Enhanced purity; Lower endotoxin spec; CHO expressed!
New Product 7268-CT
 325-CT7  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Recombinant Human CTLA-4 Fc Chimera Protein His-tag, CF


New rhCTLA-4 Available! Increased activity; Enhanced purity; Lower endotoxin spec; CHO expressed!
New Product 7268-CT
 325-CT/CF7  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Recombinant Mouse CTLA-4 Fc Chimera Protein

 434-CT10  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Recombinant Mouse CTLA-4 Fc Chimera Protein, CF

 434-CT/CF10  
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....

Recombinant Cynomolgus Monkey CTLA-4 Fc Chimera, CF

 9336-CT 
View Sizes & Prices
Catalog# Size Price Stock Quantity
Loading Information....
page of 1
Results Per Page