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CTLA-4: Products

CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA-4 is up-regulated rapidly following T cell activation and CD28 ligation. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28.

Showing 1-5 out of 5 CTLA-4 Products

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 325-CT/CF6  
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 325-CT6  
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 434-CT/CF7  
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 434-CT7  
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 7268-CT 
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