CTLA-4: Products

CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.

Showing 1-4 out of 4 CTLA-4 Products

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Human CTLA-4 Alexa Fluor® 488-conjugated Antibody


Recombinant Monoclonal Antibody
FlowFAB3252G 
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Mouse CTLA-4 Alexa Fluor® 488-conjugated Antibody

FlowFAB434G 
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Human CTLA-4 (Ipilimumab) Alexa Fluor® 488-conjugated Antibody


Recombinant Monoclonal Antibody
FlowFAB9928G 
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Human CTLA-4 Alexa Fluor® 488-conjugated Antibody

FlowIC3251G 
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