CTLA-4: Products

CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.

Showing 1-8 out of 8 CTLA-4 Products

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Recombinant Human CTLA-4 Fc Chimera His Tagged Protein


New rhCTLA-4 Available! Increased activity; Enhanced purity; Lower endotoxin spec; CHO expressed!
New Product 7268-CT
Bioactivity325-CT7  
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Recombinant Human CTLA-4 Fc Chimera Protein His-tag, CF


New rhCTLA-4 Available! Increased activity; Enhanced purity; Lower endotoxin spec; CHO expressed!
New Product 7268-CT
Bioactivity325-CT/CF7  
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Recombinant Human CTLA-4 Fc Chimera (CHO-expressed), CF

Bioactivity7268-CT1  
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Recombinant Mouse CTLA-4 Fc Chimera Protein

Bioactivity434-CT10  
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Recombinant Mouse CTLA-4 Fc Chimera Protein, CF

Bioactivity434-CT/CF10  
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Mouse CTLA-4 Antibody

B/N, CyTOF-ready, Flow, WBMAB4341  
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Mouse CTLA-4 Antibody

ELISA(Cap), WBAF4761  
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Recombinant Cynomolgus Monkey CTLA-4 Fc Chimera Protein, CF

Bioactivity9336-CT 
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