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CXCL8/IL-8: Products

CXCL8/Interleukin-8 is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. CXCL8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. CXCL8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. CXCL8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents CXCL8 interaction with CXCR1.

Showing 1-10 out of 10 CXCL8/IL-8 Products

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D8000C187  
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DY20877  
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HS8002  
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Q8000B8  
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P800015  
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DY5354  
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CA8000 
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DY22771  
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DY16081  
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For use with catalog number Q8000B
QC194 
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