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CXCL8/IL-8: Products

CXCL8/Interleukin-8 is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. CXCL8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. CXCL8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. CXCL8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents CXCL8 interaction with CXCR1.

Showing 1-12 out of 12 CXCL8/IL-8 Products

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 208-IL69  
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 208-IL/CF69  
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 618-IL5  
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 618-IL/CF5  
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 535-IN2  
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 535-IN/CF2  
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 968-IL1  
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 1608-CL/CF 
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 968-IL/CF1  
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 1608-CL 
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 2277-FL 
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 2277-FL/CF 
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