CXCR2/IL-8 RB: Products

CXCR2/IL-8 RB is a member of the CXC chemokine receptor subfamily. Similar to other chemokine receptors, it is a G protein-coupled receptor (GPCR). Human CXCR2/IL-8 RB is 360 amino acids (aa) in length with a predicted molecular weight of 41 kDa. The human protein shares 71% aa sequence identity with the mouse and rat protein. CXCR2/IL-8 RB is expressed on neutrophils and activates neutrophil chemotaxis. Similar to the closely related CXCR1/IL-8 RA, CXCR2/IL-8 RB binds and mediates CXCL8/IL-8-induced neutrophil activation. It also binds additional CXC chemokine ligands that contain an ELR aa motif. CXCR2/IL-8 RB is implicated in neurological and pulmonary inflammatory diseases and injury. As such, it is a therapeutic target of interest in inflammatory disease and cancer.

Showing 1-19 out of 19 CXCR2/IL-8 RB Products

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Human CXCR2/IL-8 RB Antibody


Clone 48311 was used by HLDA to establish CD designation
B/N, Flow, IHCMAB33129  
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Mouse CXCR2/IL-8 RB Antibody

B/N, FlowMAB216416  
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Mouse CXCR2/IL-8 RB PE-conjugated Antibody

FlowFAB2164P14  
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Mouse CXCR2/IL-8 RB APC-conjugated Antibody

FlowFAB2164A3  
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Human CXCR2/IL-8 RB PE-conjugated Antibody


Clone 48311 was used by HLDA to establish CD designation
FlowFAB331P6  
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Human CXCR2/IL-8 RB Fluorescein-conjugated Antibody


Clone 48311 was used by HLDA to establish CD designation
FlowFAB331F4  
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SB 225002


Potent and selective CXCR2 antagonist
27256  
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SB 265610


Potent CXCR2 antagonist
27243  
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Rat CXCR2/IL-8 RB Antibody

FlowMAB8110 
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Rat CXCR2/IL-8 RB PE-conjugated Antibody

FlowFAB8110P 
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Rat CXCR2/IL-8 RB APC-conjugated Antibody

FlowFAB8110A 
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Human CXCR2/IL-8 RB APC-conjugated Antibody


Clone 48311 was used by HLDA to establish CD designation
FlowFAB331A1  
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Human CXCR2/IL-8 RB PerCP-conjugated Antibody


Clone 48311 was used by HLDA to establish CD designation
FlowFAB331C 
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Mouse CXCR2/IL-8 RB PerCP-conjugated Antibody

FlowFAB2164C 
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Human CXCR2/IL-8 RB Alexa Fluor® 700-conjugated Antibody


Clone 48311 was used by HLDA to establish CD designation
FlowFAB331N 
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SB 332235


Potent CXCR2 antagonist
5671 
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Human CXCR2/IL-8 RB (AAB25880) VersaClone cDNA

RDC0027 
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Mouse CXCR2/IL-8 RB (NP_034039) VersaClone cDNA

RDC0028 
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Rat CXCR2/IL-8 RB (NP_058879) VersaClone cDNA

RDC0242 
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