CXCR4: Products

CXCR4, also known as fusin or LESTR, is a G protein-coupled receptor (GPCR) member of the CXC subfamily of chemokine receptors. Human CXCR4 is 352 amino acids (aa) in length with a predicted molecular weight of 40 kDa. The mouse and rat proteins share 91% aa sequence identity with the human protein. CXCR4 is the chemokine receptor for CXCL12. CXCR4 is a critical regulator of progenitor and stem cell mobilization and recruitment during development and during hematopoiesis. As such, antagonists of CXCR4 can be used to harvest hematopoietic stem/progenitor cells from bone marrow. Significantly, CXCR4 also acts as a co-receptor for HIV and mediates viral entry and infection of T cells. Studies on multiple tumor types implicate the CXCL12:CXCR4 axis in tumor metastasis and angiogenesis.

Showing 1-40 out of 40 CXCR4 Products

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Human CXCR4 Antibody


Recombinant Monoclonal Antibody.
B/N, FlowMAB170R 
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Human CXCR4 Antibody

B/N, Flow, IHCMAB17221  
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Human CXCR4 Antibody

B/N, FlowMAB17023  
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Mouse CXCR4 Antibody

B/N, Flow, ICC/IF, IHCMAB2165115  
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Human CXCR4 PE-conjugated Antibody

FlowFAB170P17  
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Human CXCR4 Antibody

B/N, FlowMAB17316  
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Human CXCR4 PE-conjugated Antibody

FlowFAB173P6  
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Human CXCR4 Fluorescein-conjugated Antibody

FlowFAB170F8  
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Human CXCR4 Antibody

B/NMAB1718  
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Mouse CXCR4 PE-conjugated Antibody

FlowFAB21651P6  
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AMD 3100 octahydrochloride


Highly selective CXCR4 antagonist
32999  
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Human CXCR4 APC-conjugated Antibody

FlowFAB170A3  
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Human CXCR4 APC-conjugated Antibody

FlowFAB173A1  
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Human CXCR4 Alexa Fluor® 488-conjugated Antibody

FlowFAB173G1  
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Mouse CXCR4 APC-conjugated Antibody

FlowFAB21651A2  
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Human CXCR4 Biotinylated Antibody

FlowFAB172B3  
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Human CXCR4 Biotinylated Antibody

FlowFAB170B2  
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Human CXCR4 Biotinylated Antibody

FlowFAB173B2  
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AMD 3465 hexahydrobromide


Potent and selective CXCR4 antagonist
41791  
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Mouse CXCR4 Fluorescein-conjugated Antibody

FlowFAB21651F1  
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Human CXCR4 Alexa Fluor® 700-conjugated Antibody

FlowFAB170N 
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IT1t dihydrochloride


Potent CXCR4 antagonist
4596 
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Mouse CXCR4 PerCP-conjugated Antibody

FlowFAB21651C 
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Human CXCR4 PerCP-conjugated Antibody

FlowFAB173C 
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Human CXCR4 Alexa Fluor® 700-conjugated Antibody

FlowFAB173N 
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Human CXCR4 PerCP-conjugated Antibody

FlowFAB170C 
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Human CXCR4 Alexa Fluor® 488-conjugated Antibody

FlowFAB170G 
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Feline CXCR4 Antibody

Flow, ICC/IFMAB4287 
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WZ 811


Potent CXCR2 antagonist
3951 
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TC 14012


CXCR4 antagonist; ACKR3 (CXCR7) agonist
4300 
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CTCE 9908


CXCR4 antagonist; antitumor
5130 
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ATI 2341


CXCR4 allosteric agonist
5795 
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FC 131


CXCR4 antagonist
4320 
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Human CXCR4 (NP_001008540) VersaClone cDNA

RDC0809 
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Rat CXCR4 (NP_071541) VersaClone cDNA

RDC0034 
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Feline CXCR4 (NP_00109826) VersaClone cDNA

RDC0904 
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Human CXCR4 Biotinylated MAb Sampler


1 vial each of clones 44708, 44716, 44717, and 12G5, biotinylated
FlowFABSP2B 
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Mouse CXCR4 (P70658) VersaClone cDNA

RDC0033 
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Human CXCR4 (NP_003458) VersaClone cDNA

RDC0032 
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Canine CXCR4 (NP_001041491) VersaClone cDNA

RDC1066 
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