Caspase-1: Products

Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the initiation and execution of apoptosis. They are expressed as latent zymogens and are activated by an autoproteolytic mechanism or by processing by other proteases (frequently other caspases). Human caspases can be subdivided into three functional groups: cytokine activation (caspase-1, -4, -5, and -13), apoptosis initiation (caspase-2, -8, -9, -and -10), and apoptosis execution (caspase-3, -6, and -7).

Caspases are regulated by a variety of stimili, including APAF1, CFLAR/FLIP, NOL3/ARC, and members of the inhibitor of apoptosis (IAP) family such as BIRC1/NAIP, BIRC2/cIAP-1, BIRC3/cIAP-2, BIRC4/XIAP, BIRC5/Survivin, and BIRC7/Livin. IAP activity is modulated by DIABLO/SMAC or PRSS25/HTRA2/Omi. Cell-permeable and irreversible peptide inhibitors are also available for different caspases.

Showing 1-7 out of 7 Caspase-1 Products

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Human Caspase-1/ICE Quantikine ELISA Kit

ELISADCA10014  
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Caspase-1/ICE Inhibitor Z-WEHD-FMK

FMK0029  
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Human Caspase-1 Antibody

ICC/IF, SW, WBAF62152  
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Human Caspase-1 Antibody

ICC/IF, WBMAB62151  
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Caspase-1/ICE Colorimetric Assay Kit

BF15100 
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Caspase-1/ICE Fluorometric Assay Kit

BF171001  
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Quantikine Immunoassay Control Set 775 Human Caspase-1/ICE


For use with catalog number DCA100
CtrlQC57 
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