Caspase-2: Products

Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the initiation and execution of apoptosis. They are expressed as latent zymogens and are activated by an autoproteolytic mechanism or by processing by other proteases (frequently other caspases). Human caspases can be subdivided into three functional groups: cytokine activation (caspase-1, -4, -5, and -13), apoptosis initiation (caspase-2, -8, -9, -and -10), and apoptosis execution (caspase-3, -6, and -7).

Caspases are regulated by a variety of stimili, including APAF1, CFLAR/FLIP, NOL3/ARC, and members of the inhibitor of apoptosis (IAP) family such as BIRC1/NAIP, BIRC2/cIAP-1, BIRC3/cIAP-2, BIRC4/XIAP, BIRC5/Survivin, and BIRC7/Livin. IAP activity is modulated by DIABLO/SMAC or PRSS25/HTRA2/Omi. Cell-permeable and irreversible peptide inhibitors are also available for different caspases.

Showing 1-6 out of 6 Caspase-2 Products

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Caspase-2 Inhibitor Z-VDVAD-FMK

FMK0037  
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Human/Mouse Caspase-2 Antibody

WBAF8262  
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Recombinant Human Active Caspase-2 Protein

 702-C23  
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Recombinant Human Active Caspase-2 Protein, CF

 702-C2/CF3  
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Human Caspase-2 Antibody

ICC/IFMAB7228 
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Z-VDVAD-FMK


Irreversible caspase-2 inhibitor
2165 
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