Caspase-3: Products

Caspase-3 is a widely expressed dimeric peptidase that is the major executioner caspase, the primary downstream mediator of apoptotic-associated proteolysis. Caspase-3 cleaves multiple substrates including PARP, proIL-16, PKC-gamma and -delta, proCaspases-6, -7, and -9, and beta-Catenin. Normally, it is an inactive, exclusively cytosolic homodimer. During apoptosis, however, proCaspase-3 is activated by cleavage into p20 and p12 subunits, and the p20 subunit is trimmed to yield a p17 subunit. Active Caspase-3 contains two p17 and two p12 subunits.

Showing 1-22 out of 22 Caspase-3 Products

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Human/Mouse Active Caspase-3 Antibody

ICC/IFAF83580  
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Human Caspase-3 Antibody


Recombinant Monoclonal Antibody.
ICC/IFMAB7071 
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Caspase-3 Inhibitor Z-DEVD-FMK

FMK00431  
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Human/Mouse Cleaved Caspase-3 (Asp175) Antibody

ICC/IF, WBMAB83514  
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Caspase-3 Colorimetric Assay Kit

BF310022  
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Caspase-3 Fluorometric Assay Kit

BF110014  
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Cisplatin


Potent pro-apoptotic anticancer agent; activates caspase-3
22519  
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Human Active Caspase-3 Quantikine ELISA Kit

ELISAKM3006  
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Human/Mouse Caspase-3 Antibody

IP, SW, WBAF-605-NA5  
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Recombinant Human Caspase-3 Protein, CF

 707-C3/CF5  
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Recombinant Human Caspase-3 Protein

 707-C35  
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Human Caspase-3 Antibody

WBMAB7075  
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Human/Mouse Cleaved Caspase-3 (Asp175) DuoSet IC ELISA

ELISADYC835-21  
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Human/Mouse Cleaved Caspase-3 Alexa Fluor® 488-conjugated Antibody

FlowIC835G 
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Proteome Profiler Human Apoptosis Array Kit


Contains 4 membranes - each spotted in duplicate with 35 different apoptosis antibodies
ARY00928  
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Recombinant Human Pro-Caspase-3 Protein, CF

 731-C3 
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Z-DEVD-FMK


Cell-permeable, irreversible caspase-3 inhibitor
21663  
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Apoptosis Activator 2


Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis
20981  
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AZ 10417808


Selective non-peptide caspase-3 inhibitor
21721  
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PAC 1


Activator of procaspase-3; pro-apoptotic
2581 
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PETCM


Activator of caspase-3
1758 
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Z-DQMD-FMK


Caspase-3 inhibitor
2168 
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